Cyclopeptide mushroom poisoning: A retrospective series of 204 patients

Cyclopeptide mushroom poisoning is responsible for 90%–95% of deaths from macrofungi ingestion. The main objectives of this study are to describe cases of cyclopeptide mushroom poisoning and to determine risk factors that may influence the severity/mortality of poisoned patients. We included all cas...

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Veröffentlicht in:Basic & clinical pharmacology & toxicology 2023-06, Vol.132 (6), p.533-542
Hauptverfasser: Lecot, Jérémy, Cellier, Morgane, Courtois, Arnaud, Vodovar, Dominique, Le Roux, Gaël, Landreau, Anne, Labadie, Magali, Bruneau, Chloé, Descatha, Alexis
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Sprache:eng
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Zusammenfassung:Cyclopeptide mushroom poisoning is responsible for 90%–95% of deaths from macrofungi ingestion. The main objectives of this study are to describe cases of cyclopeptide mushroom poisoning and to determine risk factors that may influence the severity/mortality of poisoned patients. We included all cases of amatoxin toxicity reported to two French Poison Centers from 2013 through 2019. We compared the severity with the Poison Severity Score (PSS) and the outcomes of patients using simple logistic regression and multinomial logistic regression. We included 204 cases of amatoxin toxicity. More than three‐quarters developed an increase in AST and/or ALT (78.1%), and over half developed a decrease in prothrombin ratio (
ISSN:1742-7835
1742-7843
DOI:10.1111/bcpt.13858