Endovascular ultrasound renal denervation to treat hypertension (RADIANCE-HTN SOLO): a multicentre, international, single-blind, randomised, sham-controlled trial

Endovascular ultrasound renal denervation to treat hypertension (RADIANCE-HTN SOLO): a multicentre, international, single-blind, randomised, sham-controlled trial

Early studies suggest that radiofrequency-based renal denervation reduces blood pressure in patients with moderate hypertension. We investigated whether an alternative technology using endovascular ultrasound renal denervation reduces ambulatory blood pressure in patients with hypertension in the ab...

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Veröffentlicht in:The Lancet (British edition) 2018-06, Vol.391 (10137), p.2335-2345
Hauptverfasser: Azizi, Michel, Schmieder, Roland E, Mahfoud, Felix, Weber, Michael A, Daemen, Joost, Davies, Justin, Basile, Jan, Kirtane, Ajay J, Wang, Yale, Lobo, Melvin D, Saxena, Manish, Feyz, Lida, Rader, Florian, Lurz, Philipp, Sayer, Jeremy, Sapoval, Marc, Levy, Terry, Sanghvi, Kintur, Abraham, Josephine, Sharp, Andrew S P, Fisher, Naomi D L, Bloch, Michael J, Reeve-Stoffer, Helen, Coleman, Leslie, Mullin, Christopher, Mauri, Laura
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
Aged
Blood Pressure Monitoring, Ambulatory
Denervation
Endovascular Procedures
Female
Humans
Hypertension
Kidney
Life Sciences
Male
Middle Aged
Renal Artery
Single-Blind Method
Treatment Outcome
Ultrasonography
Young Adult
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Beschreibung
Zusammenfassung:Early studies suggest that radiofrequency-based renal denervation reduces blood pressure in patients with moderate hypertension. We investigated whether an alternative technology using endovascular ultrasound renal denervation reduces ambulatory blood pressure in patients with hypertension in the absence of antihypertensive medications.
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(18)31082-1