Representation of gene regulation networks by hypothesis logic-based Boolean systems
Boolean Dynamical Systems (BDSs) are networks described by Boolean variables. A new representation of BDSs is presented in this article by using modal non-monotonic logic ( H ). This approach allows Boolean Networks to be represented by a set of modal formulas and therefore can be used to describe a...
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Veröffentlicht in: | The Journal of supercomputing 2023-03, Vol.79 (4), p.4556-4581 |
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Hauptverfasser: | , , , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | Boolean Dynamical Systems (BDSs) are networks described by Boolean variables. A new representation of BDSs is presented in this article by using modal non-monotonic logic (
H
). This approach allows Boolean Networks to be represented by a set of modal formulas and therefore can be used to describe and learn their properties. The study of a BDS focuses in particular on the search of stable configurations, limit cycles and unstable cycles, which help to characterize a large type of Gene Networks. In this article is presented the identification of such asymptotic properties by introduction of a new concept,
ghost extensions
. Using
ghost extensions
, it is possible to translate BDSs in propositional calculus and consequently to use SAT algorithms. |
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ISSN: | 0920-8542 1573-0484 |
DOI: | 10.1007/s11227-022-04809-5 |