Mechanical ventilation in patients with cardiogenic pulmonary edema: a sub-analysis of the LUNG SAFE study

Abstract Background Patients with acute respiratory failure caused by cardiogenic pulmonary edema (CPE) may require mechanical ventilation that can cause further lung damage. Our aim was to determine the impact of ventilatory settings on CPE mortality. Methods Patients from the LUNG SAFE cohort, a m...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of intensive care 2022-12, Vol.10 (1)
Hauptverfasser: Amado-Rodríguez, Laura, Rodríguez-Garcia, Raquel, Bellani, Giacomo, Pham, Tài, Fan, Eddy, Madotto, Fabiana, Laffey, John, Albaiceta, Guillermo, Pesenti, Antonio, Brochard, Laurent, Esteban, Andres, Gattinoni, Luciano, van Haren, Frank, Larsson, Anders, Mcauley, Danielf, Ranieri, Marco, Rubenfeld, Gordon, Taylor Thompson, B., Wrigge, Hermann, Slutsky, Arthur, Rios, Fernando, Sottiaux, Thierry, Depuydt, Pieter, Lora, Fredy, Azevedo, Luciano Cesar, Bugedo, Guillermo, Qiu, Haibo, Gonzalez, Marcos, Silesky, Juan, Cerny, Vladimir, Nielsen, Jonas, Jibaja, Manuel, Matamis, Dimitrios, Ranero, Jorge Luis, Amin, Pravin, Hashemian, S., Clarkson, Kevin, Kurahashi, Kiyoyasu, Villagomez, Asisclo, Zeggwagh, Amine Ali, Heunks, Leo, Laake, Jon Henrik, Palo, Jose Emmanuel, Do Vale Fernandes, Antero, Sandesc, Dorel, Arabi, Yaasen, Bumbasierevic, Vesna, Nin, Nicolas, Lorente, Jose, Piquilloud, Lise, Abroug, Fekri, Mcnamee, Lia, Hurtado, Javier, Bajwa, Ed, Démpaire, Gabriel, Sula, Hektor, Nunci, Lordian, Cani, Alma, Zazu, Alan, Dellera, Christian, Insaurralde, Carolina, Las Lomas, Sanatorio, Isidro, San, Alejandro, Risso, Daldin, Julio, Vinzio, Mauricio, Fernandez, Ruben, Cardonnet, Luis, Bettini, Lisandro, Bisso, Mariano Carboni, Osman, Emilio, Setten, Mariano, Lovazzano, Pablo, Alvarez, Javier, Villar, Veronica, Pozo, Norberto, Grubissich, Nicolas, Plotnikow, Gustavo, Vasquez, Daniela, Ilutovich, Santiago, Tiribelli, Norberto, Chena, Ariel, Pellegrini, Carlos, Saenz, María, Estenssoro, Elisa, Brizuela, Matias, Gianinetto, Hernan, Gomez, Pablo, Cerrato, Valeria, Bezzi, Marco, Borello, Silvina, Loiacono, Flavia, Fernandez, Adriana, Knowles, Serena, Reynolds, Claire, Inskip, Deborah, Miller, Jennene, Kong, Jing, Whitehead, Christina, Bihari, Shailesh
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Abstract Background Patients with acute respiratory failure caused by cardiogenic pulmonary edema (CPE) may require mechanical ventilation that can cause further lung damage. Our aim was to determine the impact of ventilatory settings on CPE mortality. Methods Patients from the LUNG SAFE cohort, a multicenter prospective cohort study of patients undergoing mechanical ventilation, were studied. Relationships between ventilatory parameters and outcomes (ICU discharge/hospital mortality) were assessed using latent mixture analysis and a marginal structural model. Results From 4499 patients, 391 meeting CPE criteria (median age 70 [interquartile range 59–78], 40% female) were included. ICU and hospital mortality were 34% and 40%, respectively. ICU survivors were younger (67 [57–77] vs 74 [64–80] years, p
ISSN:2052-0492
2052-0492
DOI:10.1186/s40560-022-00648-x