In vitro susceptibility of nonfermenting Gram-negative rods to meropenem-vaborbactam and delafloxacin
Meropenem-vaborbactam and delafloxacin activities were not assessed against spp. ( ), complex ( ) and ( ). A total of 106 , 57 and 100 were tested with gradient diffusion test of meropenem-vaborbactam, delafloxacin and comparators. Meropenem-vaborbactam MIC were 4 μg/ml for , 1 μg/ml for , 2 μg/ml...
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Veröffentlicht in: | Future microbiology 2023-01, Vol.18 (2), p.117-126 |
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Hauptverfasser: | , , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
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Zusammenfassung: | Meropenem-vaborbactam and delafloxacin activities were not assessed against
spp. (
),
complex (
) and
(
).
A total of 106
, 57
and 100
were tested with gradient diffusion test of meropenem-vaborbactam, delafloxacin and comparators.
Meropenem-vaborbactam MIC
were 4 μg/ml for
, 1 μg/ml for
, 2 μg/ml for
and
, and 32 μg/ml for
. Delafloxacin MIC
were 4 μg/ml for
, 0.25 μg/ml for
and
, 2 μg/ml for
, and 0.5 μg/m for
. meropenem-vaborbactam MICs were fourfold lower than meropenem for 28.3%
, 77.2%
, 53.8%
and 77.2%
.
Meropenem-vaborbactam and delafloxacin are
active against
and
. |
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ISSN: | 1746-0913 1746-0921 |
DOI: | 10.2217/fmb-2021-0278 |