In vitro susceptibility of nonfermenting Gram-negative rods to meropenem-vaborbactam and delafloxacin

Meropenem-vaborbactam and delafloxacin activities were not assessed against spp. ( ), complex ( ) and ( ). A total of 106 , 57  and 100  were tested with gradient diffusion test of meropenem-vaborbactam, delafloxacin and comparators. Meropenem-vaborbactam MIC were 4 μg/ml for , 1 μg/ml for , 2 μg/ml...

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Veröffentlicht in:Future microbiology 2023-01, Vol.18 (2), p.117-126
Hauptverfasser: Farfour, Eric, d'Epenoux, Louise Ruffier, Muggeo, Anaëlle, Alauzet, Corentine, Crémet, Lise, Moussalih, Sophie, Roux, Antoine, de Verdière, Sylvie C, Bosphore, Amélie, Corvec, Stéphane, Guillard, Thomas, Vasse, Marc
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Sprache:eng
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Zusammenfassung:Meropenem-vaborbactam and delafloxacin activities were not assessed against spp. ( ), complex ( ) and ( ). A total of 106 , 57  and 100  were tested with gradient diffusion test of meropenem-vaborbactam, delafloxacin and comparators. Meropenem-vaborbactam MIC were 4 μg/ml for , 1 μg/ml for , 2 μg/ml for and , and 32 μg/ml for . Delafloxacin MIC were 4 μg/ml for , 0.25 μg/ml for and , 2 μg/ml for , and 0.5 μg/m for . meropenem-vaborbactam MICs were fourfold lower than meropenem for 28.3% , 77.2% , 53.8% and 77.2% . Meropenem-vaborbactam and delafloxacin are active against and .
ISSN:1746-0913
1746-0921
DOI:10.2217/fmb-2021-0278