Detection of BRAFV600E by digital PCR on fine-needle aspirate enables rapid initiation of dabrafenib and trametinib in unresectable anaplastic thyroid carcinoma

Introduction Recently, targeted therapies using BRAFV600E and MEK inhibitors (dabrafenib and trametinib, respectively) have been recommended in BRAF-mutated anaplastic thyroid carcinoma (ATC). Considering the fast development of ATC, droplet digital PCR (ddPCR) performed on fine-needle aspirate (FNA...

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Veröffentlicht in:	European journal of endocrinology 2022-09, Vol.187 (3), p.K33-K38
Hauptverfasser:	Buffet, Camille, Allard, Lucie, Guillerm, Erell, Ghander, Cécile, Mathy, Elise, Lussey-Lepoutre, Charlotte, Julien, Nicolas, Touma, Eliane, Quilhot, Pauline, Godiris-Petit, Gaelle, Lacorte, Jean-Marc, Leenhardt, Laurence, Denis, Jérôme Alexandre
Format:	Artikel
Sprache:	eng
Schlagworte:	Brief Report Cervix Life Sciences MEK inhibitors Mutation Patients Thyroid carcinoma
Online-Zugang:	Volltext
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