Hydrogen-bonded supramolecular polymer micelles with pH/photothermal-responsive carmofur release and combined chemo-photothermal therapy

Hydrogen-bonded supramolecular polymer micelles with pH/photothermal-responsive carmofur release and combined chemo-photothermal therapy

Integrating biomedical applications ( e.g. , drug delivery) into supramolecular chemistry is a promising strategy. This work targets the construction of hydrogen-bonded (H-bonded) supramolecular polymeric micelles loaded with chemotherapy drugs (carmofur) and photothermal agents (IR780) for combined...

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Veröffentlicht in:Polymer chemistry 2022-02, Vol.13 (8), p.1010-1014
Hauptverfasser: Wu, Yanggui, Wang, Huiying, Liu, Qianqian, Lortie, Frédéric, Bernard, Julien, Binder, Wolfgang H., Chen, Senbin, Zhu, Jintao
Format: Artikel
Sprache:eng
Schlagworte:
Biomedical materials
Bonding agents
Chemical Sciences
Galenic pharmacology
Hydrogen bonding
Life Sciences
Micelles
Pharmaceutical sciences
Pharmacists
Polymer chemistry
Polymers
Supramolecular polymers
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Zusammenfassung:Integrating biomedical applications ( e.g. , drug delivery) into supramolecular chemistry is a promising strategy. This work targets the construction of hydrogen-bonded (H-bonded) supramolecular polymeric micelles loaded with chemotherapy drugs (carmofur) and photothermal agents (IR780) for combined chemo-photothermal therapies (CT/PTT).
ISSN:1759-9954
1759-9962
DOI:10.1039/D1PY01634B