Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo

The receptor tyrosine kinases (RTKs) expressed on the surface of endothelial cells are likely to play key roles in initiating the program of endothelial cell growth during development and subsequent vascularization during wound healing and tumorigenesis. Expression of the Tek RTK during mouse develo...

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Veröffentlicht in:Genes & development 1994-08, Vol.8 (16), p.1897-1909
Hauptverfasser: Dumont, D J, Gradwohl, G, Fong, G H, Puri, M C, Gertsenstein, M, Auerbach, A, Breitman, M L
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Sprache:eng
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