Potassium Carbonate to Unlock a GaCl 3 -Catalyzed C–H Propargylation of Arenes

Potassium Carbonate to Unlock a GaCl 3 -Catalyzed C–H Propargylation of Arenes

A gallium-catalyzed C-H propargylation of arenes using bromoallenes is described. The development of this new reaction was first hampered by a side hydroarylation process catalyzed by adventitious protons, easily generated from the solvent (1,2-dichloroethane).

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:ACS catalysis 2022-01, Vol.12 (1), p.305-315
Hauptverfasser: Vayer, Marie, Rodrigues, Sophie, Miaskiewicz, Solène, Gatineau, David, Gimbert, Yves, Gandon, Vincent, Bour, Christophe
Format: Artikel
Sprache:eng
Schlagworte:
Catalysis
Chemical Sciences
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A gallium-catalyzed C-H propargylation of arenes using bromoallenes is described. The development of this new reaction was first hampered by a side hydroarylation process catalyzed by adventitious protons, easily generated from the solvent (1,2-dichloroethane).
ISSN:2155-5435
2155-5435
DOI:10.1021/acscatal.1c03014