Variant MYST4‐CBP gene fusion in a t(10;16) acute myeloid leukaemia

Summary We report a novel fusion of the MYST4 and CBP genes in an acute myeloid leukaemia (AML)‐M4 patient exhibiting t(10;16)(q22;p13) and t(11;17)(q23;q21). The t(10;16)(q22;p13) resulted in a rearrangement, where MYST4‐CBP and CBP‐MYST4 chimaeric transcripts were products of in‐frame fusions of M...

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Veröffentlicht in:	British journal of haematology 2004-06, Vol.125 (5), p.601-604
Hauptverfasser:	Murati, Anne, Adélaïde, José, Mozziconacci, Marie‐Joëlle, Popovici, Cornel, Carbuccia, Nadine, Letessier, Anne, Birg, Françoise, Birnbaum, Daniel, Chaffanet, Max
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease acute myeloid leukaemia Artificial Gene Fusion Biological and medical sciences Cancer Chimera - genetics Chromosome aberrations Chromosomes, Human, Pair 10 - genetics Chromosomes, Human, Pair 16 - genetics Female Gene Rearrangement - genetics Hematologic and hematopoietic diseases Hematology Humans Leukemia, Myeloid - genetics Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Life Sciences Medical genetics Medical sciences MYST4‐CBP fusion transcript t(10 16) Translocation, Genetic - genetics
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