Anti-human leukocyte antigen immunization after early allograft nephrectomy

Anti-human leukocyte antigen immunization after early allograft nephrectomy

The occurrence of de novo anti-human leukocyte antigen (HLA) antibodies and donor-specific antibodies (DSAs) after early graft loss is not well known. The aims of this single-center study were to evaluate the incidence of de novo DSAs and non-DSA anti-HLA antibodies after allograft nephrectomy for e...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Transplantation 2012-05, Vol.93 (9), p.936-941
Hauptverfasser: Del Bello, Arnaud, Congy, Nicolas, Sallusto, Federico, Cardeau-Desangles, Isabelle, Fort, Marylise, Esposito, Laure, Guitard, Joelle, Cointault, Olivier, Lavayssière, Laurence, Nogier, Marie Béatrice, Game, Xavier, Blancher, Antoine, Rostaing, Lionel, Kamar, Nassim
Format: Artikel
Sprache:eng
Schlagworte:
Antibodies
Antibodies - immunology
Donors
Epitopes
Female
Follow-Up Studies
Graft Rejection - immunology
Graft Rejection - prevention & control
Graft Survival - immunology
Histocompatibility antigen HLA
HLA Antigens - immunology
Humans
Immunization
Immunization - methods
Immunosuppression
Kidney Transplantation - immunology
Kidney Transplantation - methods
Leukocytes
Life Sciences
Male
Middle Aged
Nephrectomy
Time Factors
Transplantation, Homologous
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The occurrence of de novo anti-human leukocyte antigen (HLA) antibodies and donor-specific antibodies (DSAs) after early graft loss is not well known. The aims of this single-center study were to evaluate the incidence of de novo DSAs and non-DSA anti-HLA antibodies after allograft nephrectomy for early graft loss and to seek the predictive factors for the development of DSAs. Thirty-two patients, who experienced an early graft loss (
ISSN:0041-1337
1534-6080
DOI:10.1097/TP.0b013e31824b3720