Conducting the CTD orchestra

Conducting the CTD orchestra

The carboxyl-terminal domain (CTD) of RNA polymerase II (Pol II) is post-translationally modified during gene expression. A recent study has identified a CTD kinase, Hrr25, that regulates the termination of noncoding RNA genes by recruiting Rtt103, a key termination factor.

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Bibliographische Detailangaben
Veröffentlicht in:Nature chemical biology 2019-02, Vol.15 (2), p.97-98
Hauptverfasser: Genes Robles, Carlos Mario, Coin, Frédéric
Format: Artikel
Sprache:eng
Schlagworte:
631/337/384
631/337/572
631/92/275
631/92/458
Biochemical Engineering
Biochemistry
Bioorganic Chemistry
Cell Biology
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Conducting polymers
DNA-directed RNA polymerase
Gene expression
Kinases
Life Sciences
News & Views
news-and-views
Post-translation
Ribonucleic acid
RNA
RNA polymerase
RNA polymerase II
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Beschreibung
Zusammenfassung:The carboxyl-terminal domain (CTD) of RNA polymerase II (Pol II) is post-translationally modified during gene expression. A recent study has identified a CTD kinase, Hrr25, that regulates the termination of noncoding RNA genes by recruiting Rtt103, a key termination factor.
ISSN:1552-4450
1552-4469
DOI:10.1038/s41589-018-0201-6