Intraoperative partial irradiation for highly selected patients with breast cancer: Results of the INTRAOBS prospective study

To evaluate our long-term experience on one-day breast intraoperative radiotherapy (IORT) given as sole radiation treatment to selected patients with breast cancer. Inclusion criteria of INTRAOBS study (prospective observational study) were: ER+ T1N0 unifocal ductal carcinoma; absence of lymphovascu...

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Veröffentlicht in:	Cancer radiothérapie 2020-04, Vol.24 (2), p.114-119
Hauptverfasser:	Lemanski, Claire, Bourgier, Celine, Draghici, Roxanna, Thezenas, Simon, Morel, Aurélie, Rouanet, Philippe, Colombo, Pierre-Emmanuel, Mourregot, Anne, Delmond, Laure, Fenoglietto, Pascal, Ailleres, Norbert, Azria, David, Gutowski, Marian
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Breast cancer Breast Neoplasms - mortality Breast Neoplasms - pathology Breast Neoplasms - radiotherapy Breast Neoplasms - surgery Cancer du sein Carcinoma, Ductal, Breast - mortality Carcinoma, Ductal, Breast - pathology Carcinoma, Ductal, Breast - radiotherapy Carcinoma, Ductal, Breast - surgery Cosmetics Female Humans Intraoperative Care - methods IORT Life Sciences Middle Aged Neoplasm Recurrence, Local Neoplasms, Second Primary Patient Satisfaction Patient Selection Progression-Free Survival Prospective Studies Radiothérapie intra-opératoire Recurrence Récidive Résultats esthétiques Satisfaction des patientes
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Beschreibung
Zusammenfassung:	To evaluate our long-term experience on one-day breast intraoperative radiotherapy (IORT) given as sole radiation treatment to selected patients with breast cancer. Inclusion criteria of INTRAOBS study (prospective observational study) were: ER+ T1N0 unifocal ductal carcinoma; absence of lymphovascular invasion or of extensive intraductal component (Scarff-Bloom-Richardson grade III and HER2+++ excluded). Two different linacs were used (20Gy/1 fraction): one dedicated electron linac (
ISSN:	1278-3218 1769-6658
DOI:	10.1016/j.canrad.2020.01.007