Moxifloxacin-rifampicin combination for the treatment of non-staphylococcal Gram-positive orthopedic implant-related infections

•We report a case series of 23 non-staphylococcal Gram-positive orthopedic implant-related infections treated with the moxifloxacin–rifampicin combination.•In vitro moxifloxacin was 1.5 to 11.7 times as active as levofloxacin against the non-staphylococcal Gram-positive bacteria.•We reported an 81.8...

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Veröffentlicht in:	Médecine et maladies infectieuses 2019-10, Vol.49 (7), p.540-544
Hauptverfasser:	Fily, F., Jolivet-Gougeon, A., Polard, E., Gicquel, T., Dupont, M., Verdier, M.C., Arvieux, C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - adverse effects Bacteria Biofilms Bone and joint infection Cutibacterium acnes Drug Combinations Enterococcus faecalis Female Gram-positive bacteria Gram-Positive Bacterial Infections - drug therapy Gram-Positive Bacterial Infections - etiology Hip Hip Prosthesis - adverse effects Humans Infection ostéoarticulaire Infections Levofloxacin Life Sciences Male Middle Aged Minimum inhibitory concentration Moxifloxacin Moxifloxacin - administration & dosage Moxifloxacin - adverse effects Moxifloxacine Orthopaedic implants Orthopedics Propionibacteriaceae Prostheses Prosthesis-Related Infections - drug therapy Retrospective Studies Rifampicin Rifampicine Rifampin Rifampin - administration & dosage Rifampin - adverse effects Streptococcal Infections Streptococcus Treatment Outcome
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