BNT162b2 Messenger RNA Vaccination Did Not Prevent an Outbreak of Severe Acute Respiratory Syndrome Coronavirus 2 Variant 501Y.V2 in an Elderly Nursing Home but Reduced Transmission and Disease Severity

BNT162b2 Messenger RNA Vaccination Did Not Prevent an Outbreak of Severe Acute Respiratory Syndrome Coronavirus 2 Variant 501Y.V2 in an Elderly Nursing Home but Reduced Transmission and Disease Severity

Abstract We report an outbreak of severe acute respiratory syndrome coronavirus 2 501Y.V2 in a nursing home. All nonvaccinated residents (5/5) versus half of those vaccinated with BNT162b2 (13/26) were infected. Two of 13 vaccinated versus 4 of 5 nonvaccinated residents presented severe disease. BNT...

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Veröffentlicht in:Clinical infectious diseases 2022-02, Vol.74 (3), p.517-520
Hauptverfasser: Bailly, Benoit, Guilpain, Luc, Bouiller, Kevin, Chirouze, Catherine, N’Debi, Melissa, Soulier, Alexandre, Demontant, Vanessa, Pawlotsky, Jean-Michel, Rodriguez, Christophe, Fourati, Slim
Format: Artikel
Sprache:eng
Schlagworte:
Aged
BNT162 Vaccine
COVID-19
Disease Outbreaks
Human health and pathology
Humans
Life Sciences
Microbiology and Parasitology
Nursing Homes
RNA, Messenger
SARS-CoV-2
Severity of Illness Index
Vaccination
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Zusammenfassung:Abstract We report an outbreak of severe acute respiratory syndrome coronavirus 2 501Y.V2 in a nursing home. All nonvaccinated residents (5/5) versus half of those vaccinated with BNT162b2 (13/26) were infected. Two of 13 vaccinated versus 4 of 5 nonvaccinated residents presented severe disease. BNT162b2 did not prevent the outbreak, but reduced transmission and disease severity.
ISSN:1058-4838
1537-6591
DOI:10.1093/cid/ciab446