Risk Factors of Early Mortality and Morbidity in Esophageal Atresia with Distal Tracheoesophageal Fistula: A Population-Based Cohort Study

To identify the risk factors for early mortality and morbidity in a population with distal esophageal atresia (EA)-tracheoesophageal fistula. Cohort study from a national register. Main outcomes and measures included early mortality, hospital length of stay (LoS), need for nutritional support at 1 y...

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Veröffentlicht in:The Journal of pediatrics 2021-07, Vol.234, p.99-105.e1
Hauptverfasser: Sfeir, Rony, Rousseau, Veronique, Bonnard, Arnaud, Gelas, Thomas, Aumar, Madeleine, Panait, Nicoleta, Piolat, Christian, Irtan, Sabine, Fouquet, Virginie, Lemandat, Aurelie, De Napoli, Stephan, Habonimana, Edouard, Lamireau, Thierry, Lemelle, Jean Louis, El Baz, Frederic, Talon, Isabelle, Polimerol, Marie Laurence, Allal, Hussein, Buisson, Philippe, Petit, Thierry, Louis, David, Lardy, Hubert, Schmitt, Francoise, Levard, Guillaume, Scalabre, Aurélien, Michel, Jean Luc, Jaby, Olivier, Pelatan, Cecile, De Vries, Philine, Borderon, Corinne, Fourcade, Laurent, Breaud, Jean, Pouzac, Myriam, Tolg, Cecilia, Chaussy, Yann, Ritz, Sandy Jochault, Laplace, Christophe, Drumez, Elodie, Gottrand, Frederic
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Sprache:eng
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Zusammenfassung:To identify the risk factors for early mortality and morbidity in a population with distal esophageal atresia (EA)-tracheoesophageal fistula. Cohort study from a national register. Main outcomes and measures included early mortality, hospital length of stay (LoS), need for nutritional support at 1 year of age as a proxy measure of morbidity, and complications during the first year of life. In total, 1008 patients with a lower esophageal fistula were included from January 1, 2008, to December 31, 2014. The survival rate at 3 months was 94.9%. The cumulative hospital LoS was 31.0 (17.0-64.0) days. Multivariate analysis showed that intrahospital mortality at 3 months was associated with low birth weight (OR 0.52, 95% CI [0.38-0.72], P 
ISSN:0022-3476
1097-6833
DOI:10.1016/j.jpeds.2021.02.064