Inhibition of mitochondrial permeability transition to prevent the post-cardiac arrest syndrome: a pre-clinical study

Resuscitated cardiac arrest (CA), leading to harmful cardiovascular dysfunction and multiple organ failure, includes a whole-body hypoxia-reoxygenation phenomenon. Opening of the mitochondrial permeability transition pore (mPTP) appears to be a pivotal event in ischaemia-reperfusion injury. We hypot...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	European heart journal 2011-01, Vol.32 (2), p.226-235
Hauptverfasser:	COUR, Martin, LOUFOUAT, Joseph, PAILLARD, Mélanie, AUGEUL, Lionel, GOUDABLE, Joëlle, OVIZE, Michel, ARGAUD, Laurent
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Biomarkers - metabolism Calcium - metabolism Cardiology and cardiovascular system Cardiology. Vascular system Cardiopulmonary Resuscitation Cardiotonic Agents - pharmacology Cell Respiration - physiology Cyclosporine - pharmacology Heart Arrest - physiopathology Heart Arrest - prevention & control Hemodynamics - physiology Human health and pathology Ischemic Postconditioning - methods Life Sciences Male Medical sciences Mitochondrial Membrane Transport Proteins - drug effects Myocardial Contraction Myocardial Reperfusion Injury - physiopathology Myocardial Reperfusion Injury - prevention & control Rabbits Troponin I - biosynthesis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!