Corynebacterium diphtheriae Infection in Mahajanga, Madagascar: First Case Report
Abstract Diphtheria is an infection that has been unreported for more than two decades in Mahajanga. A child, aged 4, presented with a pseudomembranous pharyngitis was associated with a dysphagia. He was from a rural municipality of Ambato Boeny at Mahajanga province and was admitted to the Pediatri...
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Veröffentlicht in: | Journal of tropical pediatrics (1980) 2021-01, Vol.67 (1) |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Abstract
Diphtheria is an infection that has been unreported for more than two decades in Mahajanga. A child, aged 4, presented with a pseudomembranous pharyngitis was associated with a dysphagia. He was from a rural municipality of Ambato Boeny at Mahajanga province and was admitted to the Pediatric Unit of the University Hospital Center. The child was not immunized against diphtheria. A throat swab was performed and cultured, from which Corynebacterium diphtheriae was identified. The strain, of biovar Mitis, was confirmed as diphtheria toxin (DT)-gene positive and produced DT (Elek test). Unfortunately, the child developed cardiac and neurological complications and died of respiratory and heart failure. |
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ISSN: | 0142-6338 1465-3664 |
DOI: | 10.1093/tropej/fmaa064 |