ISOINDOLINOTRIAZOLE DERIVATIVES: SYNTHESIS BY THE AZIDE-ALKYNE CYCLOADDITION CLICK CHEMISTRY

A novel series of isoindolinotriazole derivatives with different substituents in the triazole moiety were synthesized via copper-catalyzed cycloaddition (CuAAC) click chemistry between 2-(meta- or para-ethynylphenyl)-4,6-dimethoxyisoindolin-1-ones and several azides. The synthesized triazoles were c...

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Veröffentlicht in:Journal of advances in chemistry 2014-10, Vol.10 (7), p.2937-2943
Hauptverfasser: Rakotoarivelo, Nambinina V., Najahi, Ennaji, Perio, Pierre
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Sprache:eng
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Zusammenfassung:A novel series of isoindolinotriazole derivatives with different substituents in the triazole moiety were synthesized via copper-catalyzed cycloaddition (CuAAC) click chemistry between 2-(meta- or para-ethynylphenyl)-4,6-dimethoxyisoindolin-1-ones and several azides. The synthesized triazoles were characterized by IR, 1H NMR, 13C NMR and mass spectral techniques.
ISSN:2321-807X
2321-807X
DOI:10.24297/jac.v10i7.6797