Targeted Temperature Management for Cardiac Arrest with Nonshockable Rhythm

Patients who were comatose after resuscitation from cardiac arrest with a nonshockable rhythm were randomly assigned to moderate therapeutic hypothermia (33°C) or targeted normothermia (37°C). Therapeutic hypothermia improved survival with a favorable neurologic outcome at 90 days.

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Veröffentlicht in:The New England journal of medicine 2019-12, Vol.381 (24), p.2327-2337
Hauptverfasser: Lascarrou, Jean-Baptiste, Merdji, Hamid, Le Gouge, Amélie, Colin, Gwenhael, Grillet, Guillaume, Girardie, Patrick, Coupez, Elisabeth, Dequin, Pierre-François, Cariou, Alain, Boulain, Thierry, Brule, Noelle, Frat, Jean-Pierre, Asfar, Pierre, Pichon, Nicolas, Landais, Mickael, Plantefeve, Gaëtan, Quenot, Jean-Pierre, Chakarian, Jean-Charles, Sirodot, Michel, Legriel, Stéphane, Letheulle, Julien, Thevenin, Didier, Desachy, Arnaud, Delahaye, Arnaud, Botoc, Vlad, Vimeux, Sylvie, Martino, Frederic, Giraudeau, Bruno, Reignier, Jean
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container_issue 24
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container_title The New England journal of medicine
container_volume 381
creator Lascarrou, Jean-Baptiste
Merdji, Hamid
Le Gouge, Amélie
Colin, Gwenhael
Grillet, Guillaume
Girardie, Patrick
Coupez, Elisabeth
Dequin, Pierre-François
Cariou, Alain
Boulain, Thierry
Brule, Noelle
Frat, Jean-Pierre
Asfar, Pierre
Pichon, Nicolas
Landais, Mickael
Plantefeve, Gaëtan
Quenot, Jean-Pierre
Chakarian, Jean-Charles
Sirodot, Michel
Legriel, Stéphane
Letheulle, Julien
Thevenin, Didier
Desachy, Arnaud
Delahaye, Arnaud
Botoc, Vlad
Vimeux, Sylvie
Martino, Frederic
Giraudeau, Bruno
Reignier, Jean
description Patients who were comatose after resuscitation from cardiac arrest with a nonshockable rhythm were randomly assigned to moderate therapeutic hypothermia (33°C) or targeted normothermia (37°C). Therapeutic hypothermia improved survival with a favorable neurologic outcome at 90 days.
doi_str_mv 10.1056/NEJMoa1906661
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source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; New England Journal of Medicine
subjects Aged
Anesthesia
Body Temperature
Brain Diseases - etiology
Cardiac arrest
Cardiopulmonary Resuscitation
Coma
Coma - complications
Cooling
CPR
Female
Follow-Up Studies
Heart
Heart Arrest - complications
Heart Arrest - mortality
Heart Arrest - therapy
Heart attacks
Humans
Hyperthermia
Hypothermia
Hypothermia, Induced
Intensive care
Intensive Care Units
Life Sciences
Male
Medical prognosis
Middle Aged
Mortality
Out-of-Hospital Cardiac Arrest - therapy
Patients
Single-Blind Method
title Targeted Temperature Management for Cardiac Arrest with Nonshockable Rhythm
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