Targeted Temperature Management for Cardiac Arrest with Nonshockable Rhythm

Patients who were comatose after resuscitation from cardiac arrest with a nonshockable rhythm were randomly assigned to moderate therapeutic hypothermia (33°C) or targeted normothermia (37°C). Therapeutic hypothermia improved survival with a favorable neurologic outcome at 90 days.

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Bibliographische Detailangaben
Veröffentlicht in:	The New England journal of medicine 2019-12, Vol.381 (24), p.2327-2337
Hauptverfasser:	Lascarrou, Jean-Baptiste, Merdji, Hamid, Le Gouge, Amélie, Colin, Gwenhael, Grillet, Guillaume, Girardie, Patrick, Coupez, Elisabeth, Dequin, Pierre-François, Cariou, Alain, Boulain, Thierry, Brule, Noelle, Frat, Jean-Pierre, Asfar, Pierre, Pichon, Nicolas, Landais, Mickael, Plantefeve, Gaëtan, Quenot, Jean-Pierre, Chakarian, Jean-Charles, Sirodot, Michel, Legriel, Stéphane, Letheulle, Julien, Thevenin, Didier, Desachy, Arnaud, Delahaye, Arnaud, Botoc, Vlad, Vimeux, Sylvie, Martino, Frederic, Giraudeau, Bruno, Reignier, Jean
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Anesthesia Body Temperature Brain Diseases - etiology Cardiac arrest Cardiopulmonary Resuscitation Coma Coma - complications Cooling CPR Female Follow-Up Studies Heart Heart Arrest - complications Heart Arrest - mortality Heart Arrest - therapy Heart attacks Humans Hyperthermia Hypothermia Hypothermia, Induced Intensive care Intensive Care Units Life Sciences Male Medical prognosis Middle Aged Mortality Out-of-Hospital Cardiac Arrest - therapy Patients Single-Blind Method
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Beschreibung
Zusammenfassung:	Patients who were comatose after resuscitation from cardiac arrest with a nonshockable rhythm were randomly assigned to moderate therapeutic hypothermia (33°C) or targeted normothermia (37°C). Therapeutic hypothermia improved survival with a favorable neurologic outcome at 90 days.
ISSN:	0028-4793 1533-4406
DOI:	10.1056/NEJMoa1906661