Low-dose chest CT for diagnosing and assessing the extent of lung involvement of SARS-CoV-2 pneumonia using a semi quantitative score (Publication with Expression of Concern)

Objectives The purpose is to assess the ability of low-dose CT (LDCT) to determine lung involvement in SARS-CoV-2 pneumonia and to describe a COVID19-LDCT severity score. Materials and methods Patients with SARS-CoV-2 infection confirmed by RT-PCR were retrospectively analysed. Clinical data, the Na...

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Veröffentlicht in:PloS one 2020-11, Vol.15 (11), p.e0241407-e0241407, Article 0241407
Hauptverfasser: Leger, Thomas, Jacquier, Alexis, Barral, Pierre-Antoine, Castelli, Maxime, Finance, Julie, Lagier, Jean-Christophe, Million, Matthieu, Parola, Philippe, Brouqui, Philippe, Raoult, Didier, Bartoli, Axel, Gaubert, Jean-Yves, Habert, Paul
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Sprache:eng
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Zusammenfassung:Objectives The purpose is to assess the ability of low-dose CT (LDCT) to determine lung involvement in SARS-CoV-2 pneumonia and to describe a COVID19-LDCT severity score. Materials and methods Patients with SARS-CoV-2 infection confirmed by RT-PCR were retrospectively analysed. Clinical data, the National Early Warning Score (NEWS) and imaging features were recorded. Lung features included ground-glass opacities (GGO), areas of consolidation and crazy paving patterns. The COVID19-LDCT score was calculated by summing the score of each segment from 0 (no involvement) to 10 (severe impairment). Univariate analysis was performed to explore predictive factor of high COVID19-LDCT score. The nonparametric Mann-Whitney test was used to compare groups and a Spearman correlation used with p
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0241407