Evolution and characteristics of the use of valproate in women of childbearing age with bipolar disorder: Results from the FACE-BD cohort

•Valproate is associated with teratogenic and neurodevelopmental effects.•The use of valproate in BD women of childbearing age was studied.•The prevalence of valproate use reduced from 33% to 17% after the regulatory change.•Age

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Veröffentlicht in:	Journal of affective disorders 2020-11, Vol.276, p.963-969
Hauptverfasser:	Samalin, L., Godin, O., Olié, E., Etain, B., Henry, C., Pelletier, A., Poinso, F., Encely, L., Mazer, N., Roux, P., Loftus, J, Gard, S., Bennabi, D., Polosan, M., Schwitzer, T., Aubin, V., Schwan, R., Passerieux, C., Bougerol, T., Dubertret, C., Aouizerate, B., Haffen, E., Courtet, P., Bellivier, F., Leboyer, M., Llorca, P.M., Belzeaux, R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Affect Anticonvulsant Bipolar disorder Bipolar Disorder - drug therapy Bipolar Disorder - epidemiology Female Human health and pathology Humans Life Sciences Middle Aged Pregnancy Psychiatrics and mental health Valproate Valproic Acid - adverse effects Women of childbearing age Young Adult
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Beschreibung
Zusammenfassung:	•Valproate is associated with teratogenic and neurodevelopmental effects.•The use of valproate in BD women of childbearing age was studied.•The prevalence of valproate use reduced from 33% to 17% after the regulatory change.•Age
ISSN:	0165-0327 1573-2517
DOI:	10.1016/j.jad.2020.07.078