The European Joint Research Project UHDpulse – Metrology for advanced radiotherapy using particle beams with ultra-high pulse dose rates

•Ultra-high dose rate reduces adverse side effects in radiotherapy (FLASH effect).•Studies and implementation in practice requires accurate dose measurements.•An European joint research project was started to develop a measurement framework.•Tools for dosimetry of ultra-high pulse dose rate beams wi...

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Veröffentlicht in:Physica medica 2020-12, Vol.80, p.134-150
Hauptverfasser: Schüller, Andreas, Heinrich, Sophie, Fouillade, Charles, Subiel, Anna, De Marzi, Ludovic, Romano, Francesco, Peier, Peter, Trachsel, Maria, Fleta, Celeste, Kranzer, Rafael, Caresana, Marco, Salvador, Samuel, Busold, Simon, Schönfeld, Andreas, McEwen, Malcolm, Gomez, Faustino, Solc, Jaroslav, Bailat, Claude, Linhart, Vladimir, Jakubek, Jan, Pawelke, Jörg, Borghesi, Marco, Kapsch, Ralf-Peter, Knyziak, Adrian, Boso, Alberto, Olsovcova, Veronika, Kottler, Christian, Poppinga, Daniela, Ambrozova, Iva, Schmitzer, Claus-Stefan, Rossomme, Severine, Vozenin, Marie-Catherine
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container_title Physica medica
container_volume 80
creator Schüller, Andreas
Heinrich, Sophie
Fouillade, Charles
Subiel, Anna
De Marzi, Ludovic
Romano, Francesco
Peier, Peter
Trachsel, Maria
Fleta, Celeste
Kranzer, Rafael
Caresana, Marco
Salvador, Samuel
Busold, Simon
Schönfeld, Andreas
McEwen, Malcolm
Gomez, Faustino
Solc, Jaroslav
Bailat, Claude
Linhart, Vladimir
Jakubek, Jan
Pawelke, Jörg
Borghesi, Marco
Kapsch, Ralf-Peter
Knyziak, Adrian
Boso, Alberto
Olsovcova, Veronika
Kottler, Christian
Poppinga, Daniela
Ambrozova, Iva
Schmitzer, Claus-Stefan
Rossomme, Severine
Vozenin, Marie-Catherine
description •Ultra-high dose rate reduces adverse side effects in radiotherapy (FLASH effect).•Studies and implementation in practice requires accurate dose measurements.•An European joint research project was started to develop a measurement framework.•Tools for dosimetry of ultra-high pulse dose rate beams will be provided. UHDpulse – Metrology for advanced radiotherapy using particle beams with ultra-high pulse dose rates is a recently started European Joint Research Project with the aim to develop and improve dosimetry standards for FLASH radiotherapy, very high energy electron (VHEE) radiotherapy and laser-driven medical accelerators. This paper gives a short overview about the current state of developments of radiotherapy with FLASH electrons and protons, very high energy electrons as well as laser-driven particles and the related challenges in dosimetry due to the ultra-high dose rate during the short radiation pulses. We summarize the objectives and plans of the UHDpulse project and present the 16 participating partners.
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subjects Absorbed dose
Dosimetry
European metrology project
FLASH beams
High dose rates
Physics
Traceability
title The European Joint Research Project UHDpulse – Metrology for advanced radiotherapy using particle beams with ultra-high pulse dose rates
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