Polycyclic Aromatic Hydrocarbons promote Th22 polarization by reciprocally regulating IL-22 and IL- 17

Polycyclic Aromatic Hydrocarbons promote Th22 polarization by reciprocally regulating IL-22 and IL- 17

Background: Pollution, including polyaromatic hydrocarbons (PAH), may contribute to increased

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Bibliographische Detailangaben
Veröffentlicht in:PloS one 2015-04, Vol.10 (4)
Hauptverfasser: Ple, Coline, Fan, Ying, Yahia, Saliha Ait, Vorng, Han, Everaere, Laetitia, Chenivesse, Cécile, Balsamelli, Joanne, Azzaoui, Imane, Nadai, Patricia De, Wallaert, Benoit, Lazennec, Gwendal, Tsicopoulos, Anne
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Asthma
Benzo(a)pyrene
Cancer
CD4-Positive T-Lymphocytes
Cells, Cultured
Cytochrome P-450 CYP1A1
Down-Regulation
Female
Humans
Interleukin-17
Interleukins
JNK Mitogen-Activated Protein Kinases
Leukocytes, Mononuclear
Life Sciences
Male
Middle Aged
Nuclear Receptor Subfamily 1, Group F, Member 1
Nuclear Receptor Subfamily 1, Group F, Member 3
Phosphatidylinositol 3-Kinases
Polycyclic Aromatic Hydrocarbons
Receptors, Aryl Hydrocarbon
RNA, Messenger
Th17 Cells
Up-Regulation
Vehicle Emissions
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Beschreibung
Zusammenfassung:Background: Pollution, including polyaromatic hydrocarbons (PAH), may contribute to increased
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0122372