Bacillus Calmette-Guerin infection following intravesical instillation: Does the strain matter?

•Several strains of BCG are used for intravesical instillations in the treatment of non-muscle-invasive bladder cancer.•No difference has yet been reported in the safety profiles of the various BCG strains.•In this French nationwide retrospective survey of 40 patients, those treated with the RIVM strain were less severely ill with fewer occurrences of septic shock and ICU admission (but more pulmonary miliaries) than those instilled with other strains. Hence, the type of BCG strain and/or the instillation device used could impact the frequency and severity of subsequent BCG infections.•The batch number was reported in