Efficient synthesis of RGD-containing cyclic peptide–porphyrin conjugates by ring-closing metathesis on solid support

Efficient synthesis of RGD-containing cyclic peptide–porphyrin conjugates by ring-closing metathesis on solid support

Graphic We report the efficient solid-phase synthesis of a new family of peptidic porphyrins containing a constrained RGD moiety obtained by ring-closing metathesis.

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Veröffentlicht in:Tetrahedron letters 2004-06, Vol.45 (27), p.5295-5299
Hauptverfasser: Chaleix, Vincent, Sol, Vincent, Guilloton, Michel, Granet, Robert, Krausz, Pierre
Format: Artikel
Sprache:eng
Schlagworte:
Chemical Sciences
Metathesis
Organic chemistry
Porphyrin
RGD
Solid-phase synthesis
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Beschreibung
Zusammenfassung:Graphic We report the efficient solid-phase synthesis of a new family of peptidic porphyrins containing a constrained RGD moiety obtained by ring-closing metathesis.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2004.05.004