Genetic variability in melatonin secretion originates in the number of pinealocytes in sheep

Genetic variability in plasma melatonin concentrations in ewes results from variations in pineal weight. This study investigated whether it is due to a difference in the number of pinealocytes, or in their size. Two groups of lambs were assigned before birth to being extremes (18 High and 21 Low) by...

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Veröffentlicht in:Journal of endocrinology 2002-02, Vol.172 (2), p.397-404
Hauptverfasser: Gomez Brunet, A, Malpaux, B, Daveau, A, Taragnat, C, Chemineau, P
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Sprache:eng
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Zusammenfassung:Genetic variability in plasma melatonin concentrations in ewes results from variations in pineal weight. This study investigated whether it is due to a difference in the number of pinealocytes, or in their size. Two groups of lambs were assigned before birth to being extremes (18 High and 21 Low) by calculating their genetic value on the basis of the melatonin concentrations of their parents. Lambs were bled from 1 week of age until 14 weeks of age. Pineal gland, brain and pituitary weights, length and width of the brain, and length of the hypothalamus were recorded. A significant effect (ANOVA) of genetic group (P
ISSN:0022-0795
1479-6805
DOI:10.1677/joe.0.1720397