Characterization of the Mouse Cblc/Cbl3 Gene

The mouse Cblc/Cbl3 gene was cloned and characterized. It comprises 12 exons and encodes a putative protein of 496 amino acid residues which shares an overall 67% identity with its human ortholog; it also shares 70% of amino acid identity with mouse CBL over their conserved SH2 and Ring finger domai...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochemical and biophysical research communications 2001-01, Vol.280 (1), p.182-187
Hauptverfasser:	Fiore, Frédéric, Ollendorff, Vincent, Birnbaum, Daniel
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Cblc/Cbl3 gene Cloning, Molecular Conserved Sequence Exons Gene Expression Humans Introns Life Sciences Mice Molecular Sequence Data Oncogene Protein v-cbl Organ Specificity Proto-Oncogene Proteins c-cbl Retroviridae Proteins, Oncogenic - chemistry Retroviridae Proteins, Oncogenic - genetics Sequence Alignment Sequence Homology, Amino Acid src Homology Domains Zinc Fingers
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The mouse Cblc/Cbl3 gene was cloned and characterized. It comprises 12 exons and encodes a putative protein of 496 amino acid residues which shares an overall 67% identity with its human ortholog; it also shares 70% of amino acid identity with mouse CBL over their conserved SH2 and Ring finger domains. Mouse Cblc mRNA is expressed in embryo and adult tissues and has a rather ubiquitous distribution.
ISSN:	0006-291X 1090-2104
DOI:	10.1006/bbrc.2000.4116