Comparison of Postprandial Oleic Acid, 9c,11t CLA and 10t,12c CLA Oxidation in Healthy Moderately Overweight Subjects

Few studies report the individual effect of 9c,11t- and 10t,12c-CLA on human energy metabolism. We compared the postprandial oxidative metabolism of 9c,11t- and 10t,12c-CLA and oleic acid (9c-18:1) in 22 healthy moderately overweight volunteers. After 24 weeks supplementation with 9c,11t-, 10t,12c-C...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Lipids 2010-11, Vol.45 (11), p.1047-1051
Hauptverfasser:	Malpuech-Brugère, Corinne, Mensink, Ronald P, Loreau, Olivier, Maret, Agnès, Fernie, Claire E, Lassel, Taous S, Chardigny, Jean Michel, Scrimgeour, Charlie M, Sébédio, Jean Louis, Beaufrère, Bernard
Format:	Artikel
Sprache:	eng
Schlagworte:	13CO2 Adult Biomedical and Life Sciences Communication Conjugated linoleic acid Disease Progression Double-Blind Method Female Health Human Humans Isomerism Life Sciences Linoleic Acids, Conjugated - administration & dosage Linoleic Acids, Conjugated - chemistry Linoleic Acids, Conjugated - metabolism Linoleic Acids, Conjugated - pharmacokinetics Lipid Metabolism - drug effects Lipidology Male Medical Biochemistry Medicinal Chemistry Microbial Genetics and Genomics Middle Aged Neurochemistry Nutrition Oleic Acid - administration & dosage Oleic Acid - chemistry Oleic Acid - metabolism Oleic Acid - pharmacokinetics Overweight - metabolism Oxidation Oxidation-Reduction Placebos Postprandial Period
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Few studies report the individual effect of 9c,11t- and 10t,12c-CLA on human energy metabolism. We compared the postprandial oxidative metabolism of 9c,11t- and 10t,12c-CLA and oleic acid (9c-18:1) in 22 healthy moderately overweight volunteers. After 24 weeks supplementation with 9c,11t-, 10t,12c-CLA or 9c-18:1 (3 g/day), subjects consumed a single oral bolus of the appropriate [1-¹³C]-labeled fatty acid. 8 h post-dose, cumulative oxidation was similar for 9c-18:1 and 10t,12c (P = 0.66), but significantly higher for 9c,11t (P < 0.01).
ISSN:	0024-4201 1558-9307
DOI:	10.1007/s11745-010-3480-6