Copper-Catalyzed Domino Route to Natural Nostoclides and Analogues: A Total Synthesis of Nostoclides I and II

Copper-Catalyzed Domino Route to Natural Nostoclides and Analogues: A Total Synthesis of Nostoclides I and II

An original and convenient domino route to natural nostoclides I and II has been developed using a two‐step sequence consisting of a copper‐catalyzed tandem reaction associated with Suzuki cross‐coupling. The methodology employed for this total synthesis appeared to be an interesting and sufficientl...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Advanced synthesis & catalysis 2013-10, Vol.355 (14-15), p.2936-2941
Hauptverfasser: Ngi, Samuel Inack, Petrignet, Julien, Duwald, Romain, El Hilali, El Mostafa, Abarbri, Mohamed, Duchêne, Alain, Thibonnet, Jérôme
Format: Artikel
Sprache:eng
Schlagworte:
Catalysis
copper catalysis
domino reactions
heterocyclic compounds
Life Sciences
nostoclides
total synthesis
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:An original and convenient domino route to natural nostoclides I and II has been developed using a two‐step sequence consisting of a copper‐catalyzed tandem reaction associated with Suzuki cross‐coupling. The methodology employed for this total synthesis appeared to be an interesting and sufficiently flexible tool to allow the synthesis of numerous analogues of these nostoclides.
ISSN:1615-4150
1615-4169
DOI:10.1002/adsc.201300459