Cation Tuning of Supramolecular Gel Properties: A New Paradigm for Sustained Drug Delivery

Hydrogels formed by the self‐assembly of low‐molecular‐weight gelators (LMWGs) are promising scaffolds for drug‐delivery applications. A new biocompatible hydrogel, resulting from the self‐assembly of nucleotide‐lipid salts can be safely injected in vivo. The resulting hydrogel provides sustained‐re...

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Veröffentlicht in:	Advanced materials (Weinheim) 2017-04, Vol.29 (13), p.np-n/a
Hauptverfasser:	Ramin, Michael A., Sindhu, Kotagudda Ranganath, Appavoo, Ananda, Oumzil, Khalid, Grinstaff, Mark W., Chassande, Olivier, Barthélémy, Philippe
Format:	Artikel
Sprache:	eng
Schlagworte:	amphiphiles Biocompatibility Bioengineering Biomaterials Cations drug delivery Drug delivery systems Hydrogels Life Sciences low‐molecular‐weight gels Materials science Proteins Scaffolds Self assembly supramolecular assemblies sustained release Tuning
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Beschreibung
Zusammenfassung:	Hydrogels formed by the self‐assembly of low‐molecular‐weight gelators (LMWGs) are promising scaffolds for drug‐delivery applications. A new biocompatible hydrogel, resulting from the self‐assembly of nucleotide‐lipid salts can be safely injected in vivo. The resulting hydrogel provides sustained‐release of protein for more than a week.
ISSN:	0935-9648 1521-4095
DOI:	10.1002/adma.201605227