Heat shock during in vitro maturation induces chromatin modifications in the bovine embryo

Heat stress compromises bovine oocyte developmental competence, but the effects of high temperature during oocyte maturation on embryo chromatin organization is unknown. In this study bovine oocytes were exposed to heat shock (41°C) for 12 h during in vitro maturation and then submitted to in vitro...

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Veröffentlicht in:Reproduction (Cambridge, England) England), 2019-10, Vol.158 (4), p.313-322
Hauptverfasser: Camargo, Luiz Sergio Almeida, Aguirre-Lavin, Tiphaine, Adenot, Pierre, Araujo, Thamiris Dornelas, Mendes, Vivian Rachel Araujo, Louro, Iuri Drumond, Beaujean, Nathalie, Souza, Eliza Diniz
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Sprache:eng
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Zusammenfassung:Heat stress compromises bovine oocyte developmental competence, but the effects of high temperature during oocyte maturation on embryo chromatin organization is unknown. In this study bovine oocytes were exposed to heat shock (41°C) for 12 h during in vitro maturation and then submitted to in vitro fertilization. The heat shock did not affect (P > 0.05) the cleavage but reduced (P  0.05) on total cell number was found, but the heat shock increased (P 
ISSN:1470-1626
1741-7899
DOI:10.1530/REP-19-0245