Long-term fatigue and quality of life among epithelial ovarian cancer survivors: a GINECO case/control VIVROVAIRE I study

Few data are available on long-term fatigue (LTF) and quality of life (QoL) among epithelial ovarian cancer survivors (EOCS). In this case–control study, we compared LTF, symptoms and several QoL domains in EOCS relapse-free ≥3years after first-line treatment and age-matched healthy women. EOCS were...

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Veröffentlicht in:	Annals of oncology 2019-05, Vol.30 (5), p.845-852
Hauptverfasser:	Joly, F., Ahmed-Lecheheb, D., Kalbacher, E., Heutte, N., Clarisse, B., Grellard, J.M., Gernier, F., Berton-Rigaud, D., Tredan, O., Fabbro, M., Savoye, A.M., Kurtz, J.E., Alexandre, J., Follana, P., Delecroix, V., Dohollou, N., Roemer-Becuwe, C., De Rauglaudre, G., Lortholary, A., Prulhiere, K., Lesoin, A., Zannetti, A., N’Guyen, S., Trager-Maury, S., Chauvenet, L., Abadie Lacourtoisie, S., Gompel, A., Lhommé, C., Floquet, A., Pautier, P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Anxiety - epidemiology Anxiety - etiology Cancer Cancer Survivors - statistics & numerical data cancer treatment Carcinoma, Ovarian Epithelial - epidemiology Carcinoma, Ovarian Epithelial - physiopathology Carcinoma, Ovarian Epithelial - psychology Carcinoma, Ovarian Epithelial - therapy Case-Control Studies chronic fatigue Combined Modality Therapy Cross-Sectional Studies Depression - epidemiology Depression - etiology epithelial ovarian cancer Fatigue - epidemiology Fatigue - etiology Female France - epidemiology Humans Life Sciences long-term survivorship Middle Aged Ovarian Neoplasms - epidemiology Ovarian Neoplasms - physiopathology Ovarian Neoplasms - psychology Ovarian Neoplasms - therapy quality of life Quality of Life - psychology Surveys and Questionnaires Young Adult
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Zusammenfassung:	Few data are available on long-term fatigue (LTF) and quality of life (QoL) among epithelial ovarian cancer survivors (EOCS). In this case–control study, we compared LTF, symptoms and several QoL domains in EOCS relapse-free ≥3years after first-line treatment and age-matched healthy women. EOCS were recruited from 25 cooperative GINECO centers in France. Controls were randomly selected from the electoral rolls. All participants completed validated self-reported questionnaires: fatigue (FACIT-F), QoL (FACT-G/O), neurotoxicity (FACT-Ntx), anxiety/depression (HADS), sleep disturbance (ISI), and physical activity (IPAQ). Severe LTF (SLTF) was defined as a FACIT-F score
ISSN:	0923-7534 1569-8041
DOI:	10.1093/annonc/mdz074