Antipseudomonal activity enhancement of luminescent iridium(iii) dipyridylamine complexes under visible blue light
Cyclometallated iridium(iii) dipyridylamine complexes present antibacterial activity against P. aeruginosa, a highly resistant pathogenic bacterium. This activity is increased when the complex is conjugated to biotin, a bacterial nutrient, and a MIC of 4 μM (4 μg mL ) has been observed. The irradiat...
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Veröffentlicht in: | Metallomics 2017-12, Vol.9 (12), p.1820-1827 |
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Hauptverfasser: | , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Cyclometallated iridium(iii) dipyridylamine complexes present antibacterial activity against P. aeruginosa, a highly resistant pathogenic bacterium. This activity is increased when the complex is conjugated to biotin, a bacterial nutrient, and a MIC of 4 μM (4 μg mL
) has been observed. The irradiation of P. aeruginosa cultures with blue LED light potentiates the anti-bacterial activities of these iridium(iii) complexes when they are conjugated to a glycoside. |
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ISSN: | 1756-5901 1756-591X |
DOI: | 10.1039/c7mt00262a |