Bioadhesive giant vesicles for monitoring hydroperoxidation in lipid membranes

Osmotic stresses, protein insertion or lipid oxidation lead to area increase of self-assembled lipid membranes. However, methods to measure membrane expansion are scarce. Challenged by recent progress on the control of phospholipid hydroperoxidation, we introduce a method to quantitatively evaluate...

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Veröffentlicht in:	Soft matter 2015-01, Vol.11 (30), p.5995-5998
Hauptverfasser:	Aoki, P H B, Schroder, A P, Constantino, C J L, Marques, C M
Format:	Artikel
Sprache:	eng
Schlagworte:	Condensed Matter Insertion Lipid Bilayers - chemistry Lipid Bilayers - metabolism Lipid Peroxidation - genetics Lipids Membrane Lipids - chemistry Membrane Lipids - metabolism Membranes Monitoring Osmotic Pressure Oxidation Phosphatidylcholines - metabolism Phospholipids Phospholipids - chemistry Phospholipids - metabolism Physics Proteins Soft Condensed Matter Unilamellar Liposomes - chemistry Unilamellar Liposomes - metabolism Vesicles
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Beschreibung
Zusammenfassung:	Osmotic stresses, protein insertion or lipid oxidation lead to area increase of self-assembled lipid membranes. However, methods to measure membrane expansion are scarce. Challenged by recent progress on the control of phospholipid hydroperoxidation, we introduce a method to quantitatively evaluate membrane area increase based on the bio-adhesion of Giant Unilamellar Vesicles.
ISSN:	1744-683X 1744-6848
DOI:	10.1039/c5sm01019e