Facile and Efficient Control of Bioadhesion on Poly(dimethylsiloxane) by Using a Biomimetic Approach

An antiadhesive nanofilm has been designed and prepared in one step in water onto commercial poly(dimethylsiloxane) (PDMS) by mimicking the external region of cell membranes. The resulting biomimetic surfaces are effective in suppressing protein adsorption as well as bacterial and mammalian cell adh...

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Veröffentlicht in:	Angewandte Chemie International Edition 2011-11, Vol.50 (46), p.10871-10874
Hauptverfasser:	Mussard, Windy, Kebir, Nasreddine, Kriegel, Irène, Estève, Marc, Semetey, Vincent
Format:	Artikel
Sprache:	eng
Schlagworte:	Adsorption Animals Biomimetic Materials - chemistry Cell Adhesion Cell Line Cell Membrane - chemistry Chemical Sciences Dimethylpolysiloxanes - chemistry Dogs Escherichia coli - physiology Medicinal Chemistry Methylcellulose - chemistry monolayers Nanostructures - chemistry Polymers surface chemistry
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Beschreibung
Zusammenfassung:	An antiadhesive nanofilm has been designed and prepared in one step in water onto commercial poly(dimethylsiloxane) (PDMS) by mimicking the external region of cell membranes. The resulting biomimetic surfaces are effective in suppressing protein adsorption as well as bacterial and mammalian cell adhesion.
ISSN:	1433-7851 1521-3773
DOI:	10.1002/anie.201101029