Extended photo-induced endosome-like structures in giant vesicles promoted by block-copolymer nanocarriers

Upon irradiation, the photosensitizer pheophorbide-a causes dramatic morphological transitions in giant unilamellar lipid vesicles. This endocytosis-like process occurs only when the photoactive species are encapsulated in a copolymer nanocarrier and strictly depends on the chemical nature of the co...

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Veröffentlicht in:Nanoscale 2018-01, Vol.10 (33), p.15442-15446
Hauptverfasser: Montis, C, Till, U, Vicendo, P, Roux, C, Mingotaud, A-F, Violleau, F, Demazeau, M, Berti, D, Lonetti, B
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Sprache:eng
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Zusammenfassung:Upon irradiation, the photosensitizer pheophorbide-a causes dramatic morphological transitions in giant unilamellar lipid vesicles. This endocytosis-like process occurs only when the photoactive species are encapsulated in a copolymer nanocarrier and strictly depends on the chemical nature of the copolymer. Altogether, these results open up new perspectives in the field of photo-chemical internalization mediated by nanoassemblies.
ISSN:2040-3364
2040-3372
DOI:10.1039/c8nr04355h