Prevalence and Antimicrobial Resistance of Mycoplasma genitalium Infection Among Women Living With Human Immunodeficiency Virus in South Africa: A Prospective Cohort Study

This prospective cohort study of 622 women living with human immunodeficiency virus (HIV) from Johannesburg (2012) detected Mycoplasma genitalium in 7.4% (95% confidence interval [CI]: 5.5–9.7, 46/622), with detection more likely with lower CD4 counts(adjusted odds ratio [AOR] 1.02 per 10 cells/μL d...

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Veröffentlicht in:Clinical infectious diseases 2019-08, Vol.69 (5), p.873-876
Hauptverfasser: Ong, Jason J., Magooa, Mahlape Precious, Chikandiwa, Admire, Kelly, Helen, Didelot, Marie-Noelle, Muller, Etienne E., Maseko, Venessa, Segondy, Michel, Delany-Moretlwe, Sinead, Kularatne, Ranmini, Mayaud, Philippe
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Sprache:eng
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Zusammenfassung:This prospective cohort study of 622 women living with human immunodeficiency virus (HIV) from Johannesburg (2012) detected Mycoplasma genitalium in 7.4% (95% confidence interval [CI]: 5.5–9.7, 46/622), with detection more likely with lower CD4 counts(adjusted odds ratio [AOR] 1.02 per 10 cells/μL decrease, 95% CI: 1.00–1.03) and higher plasma HIV-1 RNA (AOR 1.15 per log copies/mL increase, 95% CI: 1.03–1.27). No mutations for macrolide/quinolone resistance was detected.
ISSN:1058-4838
1537-6591
DOI:10.1093/cid/ciz045