Antiprotozoal properties of Indonesian medicinal plant extracts

Antiprotozoal properties of Indonesian medicinal plant extracts

[Display omitted] Tithonia diversifolia, Cyclea barbata, Tinospora crispa, Arcangelisia flava, Pycnarrhena cauliflora are plants used in Indonesia for the traditional treatment of malaria. In the search for new antiparasitic drugs, the parts traditionally used of these 5 plants were extracted with e...

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Veröffentlicht in:Journal of herbal medicine 2018-03, Vol.11, p.46-52
Hauptverfasser: Ramadani, Arba P., Paloque, Lucie, Belda, Hugo, Tamhid, Hady Anshory, Masriani, Jumina, Augereau, Jean-Michel, Valentin, Alexis, Wijayanti, Mahardika Agus, Mustofa, Benoit-Vical, Françoise
Format: Artikel
Sprache:eng
Schlagworte:
Antiparasitic drugs
Chemical Sciences
Indonesia
Medicinal Chemistry
Plasmodium falciparum
Traditional medicine
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Zusammenfassung:[Display omitted] Tithonia diversifolia, Cyclea barbata, Tinospora crispa, Arcangelisia flava, Pycnarrhena cauliflora are plants used in Indonesia for the traditional treatment of malaria. In the search for new antiparasitic drugs, the parts traditionally used of these 5 plants were extracted with ethanol and then fractionated with various solvents and evaluated in vitro against Plasmodium falciparum and also against Babesia divergens and Leishmania infantum. Seven crude plant extracts out of 25 tested displayed high antimalarial activities with IC50 
ISSN:2210-8033
2210-8041
DOI:10.1016/j.hermed.2017.06.004