Pressure-temperature phase diagram of the dimorphism of the anti-inflammatory drug nimesulide

[Display omitted] Understanding the phase behavior of active pharmaceutical ingredients is important for formulations of dosage forms and regulatory reasons. Nimesulide is an anti-inflammatory drug that is known to exhibit dimorphism; however up to now its stability behavior was not clear, as few th...

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Veröffentlicht in:International journal of pharmaceutics 2017-06, Vol.525 (1), p.54-59
Hauptverfasser: Barrio, M., Huguet, J., Robert, B., Rietveld, I.B., Céolin, R., Tamarit, J.Ll
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Sprache:eng
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