A New Versatile Synthesis of Macrotricyclic Tetraazacycloalkane-Based Ligands from Bis-aminal Derivatives

A New Versatile Synthesis of Macrotricyclic Tetraazacycloalkane-Based Ligands from Bis-aminal Derivatives

A new powerful synthesis of symmetrical (two‐step) or dissymmetrical (three‐step) macrotricyclic cyclen‐ or cyclam‐based ligands is reported. In this procedure, the starting materials are bis‐aminals derived from condensation of cyclen or cyclam with glyoxal. The two macrocyclic subunits are linked...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:European journal of organic chemistry 2003-08, Vol.2003 (16), p.3047-3050
Hauptverfasser: Develay, Stéphanie, Tripier, Raphaël, Chuburu, Françoise, Le Baccon, Michel, Handel, Henri
Format: Artikel
Sprache:eng
Schlagworte:
Alkylation
Amines
Bis-aminals
Chemical Sciences
Nitrogen heterocycles
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A new powerful synthesis of symmetrical (two‐step) or dissymmetrical (three‐step) macrotricyclic cyclen‐ or cyclam‐based ligands is reported. In this procedure, the starting materials are bis‐aminals derived from condensation of cyclen or cyclam with glyoxal. The two macrocyclic subunits are linked by two aromatic spacers through nitrogen atoms. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003)
ISSN:1434-193X
1099-0690
DOI:10.1002/ejoc.200300188