Pregnancy outcomes in simultaneous pancreas and kidney transplant recipients: a national French survey study

Summary Simultaneous pancreas and kidney transplantation (SPK) is currently the best therapeutic option for patients with type 1 diabetes and terminal renal failure. Renal transplantation restores fertility enabling women to pursue pregnancies. However, scarcity of available data on pregnancy outcom...

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Veröffentlicht in:Transplant international 2017-09, Vol.30 (9), p.893-902
Hauptverfasser: Normand, Gabrielle, Brunner, Flora, Badet, Lionel, Buron, Fanny, Catton, Marielle, Massardier, Jérôme, Esposito, Laure, Grimbert, Philippe, Mourad, Georges, Serre, Jean E., Caillard, Sophie, Karam, Georges, Cantarovich, Diego, Morelon, Emmanuel, Thaunat, Olivier
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Sprache:eng
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Zusammenfassung:Summary Simultaneous pancreas and kidney transplantation (SPK) is currently the best therapeutic option for patients with type 1 diabetes and terminal renal failure. Renal transplantation restores fertility enabling women to pursue pregnancies. However, scarcity of available data on pregnancy outcomes in SPK impedes fair medical counseling. Medical files of all pregnancies that lasted ≥3 months among recipients of functional SPK performed between 1990 and 2015 in France were retrospectively analyzed. Twenty‐six pregnancies in 22 SPK recipients were identified. Main maternal complications included gestational hypertension (53.8%) and infections (50%). Cesarean section was performed in 73% of cases. Overall fetal survival was 92.6% with a mean gestational age of 34.2 ± 3 weeks. Four children (16.7% of live births) had a birth weight
ISSN:0934-0874
1432-2277
DOI:10.1111/tri.12983