Versatile Microfluidic Approach to Crystallization
We present a simple and easy-to-use microfluidic setup for the crystallization of mineral, organic, and biological materials. After briefly presenting the hydrodynamic properties of the setup, we test and validate it with viscous media by crystallizing a protein in an aqueous solution of PEG. We obt...
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Veröffentlicht in: | Organic process research & development 2015-12, Vol.19 (12), p.1837-1841 |
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Hauptverfasser: | , , , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | We present a simple and easy-to-use microfluidic setup for the crystallization of mineral, organic, and biological materials. After briefly presenting the hydrodynamic properties of the setup, we test and validate it with viscous media by crystallizing a protein in an aqueous solution of PEG. We obtain nucleation data in nanocrystallizers using a droplet-based method and precisely controlling input flows to test different crystallization conditions. |
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ISSN: | 1083-6160 1520-586X |
DOI: | 10.1021/acs.oprd.5b00122 |