Asymmetric hydrogenation of 2,3-dihydro-1H-inden-1-one oxime and derivatives
[Display omitted] Asymmetric hydrogenation of 2,3-dihydro-1H-inden-1-one oxime and derivatives to produce the corresponding optically active amine has been performed in the presence of rhodium and iridium catalysts. The optimization of neutral rhodium based catalytic systems by varying the operating...
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| Veröffentlicht in: | Tetrahedron: asymmetry 2016-04, Vol.27 (6), p.268-273 |
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| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
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| Online-Zugang: | Volltext |
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| Zusammenfassung: | [Display omitted]
Asymmetric hydrogenation of 2,3-dihydro-1H-inden-1-one oxime and derivatives to produce the corresponding optically active amine has been performed in the presence of rhodium and iridium catalysts. The optimization of neutral rhodium based catalytic systems by varying the operating conditions and the ligand around the metallic centre led to high conversions with moderate enantiomeric excesses. |
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| ISSN: | 0957-4166 1362-511X 0957-4166 |
| DOI: | 10.1016/j.tetasy.2016.02.005 |