Magnetic resonance enterography is feasible and reliable in multicenter clinical trials in patients with Crohn's disease, and may help select subjects with active inflammation

Summary Background Reliable tools for patient selection are critical for clinical drug trials. Aim To evaluate a consensus‐based, standardised magnetic resonance enterography (MRE) protocol for selecting patients for inclusion in Crohn's disease (CD) multicenter clinical trials. Methods This st...

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Veröffentlicht in:	Alimentary Pharmacology & Therapeutics (Suppl) 2016-01, Vol.43 (1), p.61-72
Hauptverfasser:	Coimbra, A. J. F., Rimola, J., O'Byrne, S., Lu, T. T., Bengtsson, T., Crespigny, A., Luca, D., Rutgeerts, P., Bruining, D. H., Fidler, J. L., Sandborn, W. J., Santillan, C. S., Higgins, P. D. R., Al‐Hawary, M. M., Vermeire, S., Vanbeckevoort, D., Vanslembrouck, R., Peyrin‐Biroulet, L., Laurent, V., Herrmann, K. A., Panes, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Colon - pathology Crohn Disease - pathology Endoscopy, Gastrointestinal - methods Endoscopy, Gastrointestinal - standards Female Humans Ileum - pathology Inflammation - pathology Life Sciences Magnetic Resonance Spectroscopy - methods Magnetic Resonance Spectroscopy - standards Male Middle Aged Multicenter Studies as Topic - methods Patient Selection Reproducibility of Results
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Zusammenfassung:	Summary Background Reliable tools for patient selection are critical for clinical drug trials. Aim To evaluate a consensus‐based, standardised magnetic resonance enterography (MRE) protocol for selecting patients for inclusion in Crohn's disease (CD) multicenter clinical trials. Methods This study recruited 20 patients [Crohn's Disease Activity Index (CDAI) scores:
ISSN:	0269-2813 0953-0673 1365-2036
DOI:	10.1111/apt.13453