Incidence and impact of atrial arrhythmias on thrombotic events in MPNs

Incidence and impact of atrial arrhythmias on thrombotic events in MPNs

Atrial arrhythmias (AA) induce a high rate of thromboses and require vitamin K antagonists (VKA) or direct anticoagulants (DOAC) prescriptions. Essential thrombocythemia (ET) and polycythemia vera (PV) are also pro-thrombotic diseases. The prevention of thromboses is based on the association of cyto...

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Veröffentlicht in:Annals of hematology 2018-01, Vol.97 (1), p.101-107
Hauptverfasser: Mahé, Kristell, Delluc, Aurélien, Chauveau, Aurélie, Castellant, Philippe, Mottier, Dominique, Dalbies, Florence, Berthou, Christian, Guillerm, Gaëlle, Lippert, Eric, Ianotto, Jean-Christophe
Format: Artikel
Sprache:eng
Schlagworte:
Anticoagulants
Blood cancer
Cardiac arrhythmia
Hematology
Immunology
Life Sciences
Medicine
Medicine & Public Health
Oncology
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Zusammenfassung:Atrial arrhythmias (AA) induce a high rate of thromboses and require vitamin K antagonists (VKA) or direct anticoagulants (DOAC) prescriptions. Essential thrombocythemia (ET) and polycythemia vera (PV) are also pro-thrombotic diseases. The prevention of thromboses is based on the association of cytoreductive drug and low-dose aspirin (LDA). We studied the incidence and complications of AA among patients with ET or PV. We identified 96/713 patients (13.5%) carrying AA. These patients were older (median 72.1 vs. 61.3 years old, p  
ISSN:0939-5555
1432-0584
DOI:10.1007/s00277-017-3164-x