Opinion of the Scientific Committee on Consumer Safety (SCCS) – Final version of the opinion on Phenoxyethanol in cosmetic products
The SCCS considers 2-phenoxyethanol safe for use as a preservative with a maximum concentration of 1.0%, taking into account the information provided. The toxicokinetics default factor of 4.0 can be reduced to 1.0 yielding a minimum Margin of Safety (MoS) of 25 instead of 100 for the safety assessme...
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Veröffentlicht in: | Regulatory toxicology and pharmacology 2016-12, Vol.82, p.156-156 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | The SCCS considers 2-phenoxyethanol safe for use as a preservative with a maximum concentration of 1.0%, taking into account the information provided.
The toxicokinetics default factor of 4.0 can be reduced to 1.0 yielding a minimum Margin of Safety (MoS) of 25 instead of 100 for the safety assessment of 2-phenoxyethanol.
Therefore, the MoS of about 50 for children also covers this specific age group who might be higher exposed to 2-phenoxyethanol than adults.
This Opinion does not take into account exposure from sources other than cosmetics.
•The SCCS considers 2-phenoxyethanol safe for use as a preservative with a maximum concentration of 1.0%.•The Margin of Safety (MoS) of about 50 for children also covers this specific age group.•This Opinion does not take into account exposure from sources other than cosmetics. |
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ISSN: | 0273-2300 1096-0295 |
DOI: | 10.1016/j.yrtph.2016.11.007 |