Biological-like vesicular structures self-assembled from DNA-block copolymers

Biological-like vesicular structures self-assembled from DNA-block copolymers

The polymer modification of short nucleotide sequences has been achieved for future use as self-assembled biologically active structures with sizes in the nanometre range. Co-assembly of the resulting DNA-based amphiphilic block copolymers with native proteins demonstrates the self-assembly of biolo...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2012-01, Vol.48 (20), p.2615-2617
Hauptverfasser: Cottenye, Nicolas, Syga, Marie-Isabel, Nosov, Sergey, Müller, Axel H E, Ploux, Lydie, Vebert-Nardin, Corinne
Format: Artikel
Sprache:eng
Schlagworte:
Alkenes - chemistry
Biocompatible Materials - chemistry
Chemical communication
Chemical Sciences
DNA - chemistry
Magnetic Resonance Spectroscopy
Microscopy, Electron, Transmission
Molecular Structure
Physics
Polymers - chemical synthesis
Polymers - chemistry
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Zusammenfassung:The polymer modification of short nucleotide sequences has been achieved for future use as self-assembled biologically active structures with sizes in the nanometre range. Co-assembly of the resulting DNA-based amphiphilic block copolymers with native proteins demonstrates the self-assembly of biological-like vesicular structures.
ISSN:1359-7345
1364-548X
DOI:10.1039/c2cc17487a