Longitudinal imaging in biological tissues with a single laser shot correlation system
We demonstrate the potential of a new optical imaging system to directly obtain a longitudinal slice of a biological sample. The system, based on a single-shot optical correlator, operates a time-to-space conversion and an optical time-gating by sum-frequency generation in a nonlinear crystal. Owing...
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Veröffentlicht in: | Optics express 2002-01, Vol.10 (1), p.35-40 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | We demonstrate the potential of a new optical imaging system to directly obtain a longitudinal slice of a biological sample. The system, based on a single-shot optical correlator, operates a time-to-space conversion and an optical time-gating by sum-frequency generation in a nonlinear crystal. Owing to the high speed acquisition of the technique, internal structures of in-vivo tissues can be imaged at video rate.With this apparatus, we recorded longitudinal images of ex vivo mouse ear and in vivo human skin with a depth resolution of approximately 15 microm. |
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ISSN: | 1094-4087 1094-4087 |
DOI: | 10.1364/OE.10.000035 |